(1S,2S)-2-(NAPHTHALENE-2,3-DICARBOXIMIDO)CYCLOHEXANECARBOXYLIC ACID - Names and Identifiers
Name | (1S,2S)-2-(1,3-dioxobenzo[f]isoindol-2-yl)cyclohexanecarboxylic acid
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Synonyms | LogP N-[(1S,2S)-2-CARBOXYCYCLOHEXYL]NAPHTHALENE-2,3-DICARBOXIMIDE (1S,2S)-2-(Naphthalene-2,3-dicarboximido)cyclohexanecarboxylic Acid (1S,2S)-2-(NAPHTHALENE-2,3-DICARBOXIMIDO)CYCLOHEXANECARBOXYLIC ACID (1S,2S)-2-(1,3-dioxobenzo[f]isoindol-2-yl)cyclohexanecarboxylic acid (1S,2S)-2-(1,3-Dioxo-1H-benzo[f]isoindol-2(3H)-yl)cyclohexanecarboxylic acid
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CAS | 642995-16-2
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InChI | InChI=1/C19H17NO4/c21-17-14-9-11-5-1-2-6-12(11)10-15(14)18(22)20(17)16-8-4-3-7-13(16)19(23)24/h1-2,5-6,9-10,13,16H,3-4,7-8H2,(H,23,24)/t13-,16-/m0/s1 |
(1S,2S)-2-(NAPHTHALENE-2,3-DICARBOXIMIDO)CYCLOHEXANECARBOXYLIC ACID - Physico-chemical Properties
Molecular Formula | C19H17NO4
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Molar Mass | 323.34 |
Density | 1.412g/cm3 |
Boling Point | 554.602°C at 760 mmHg |
Flash Point | 289.213°C |
Solubility | very slightly in Chloroform |
Vapor Presure | 0mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
Storage Condition | 2-8℃ |
Refractive Index | 1.688 |
(1S,2S)-2-(NAPHTHALENE-2,3-DICARBOXIMIDO)CYCLOHEXANECARBOXYLIC ACID - Introduction
(1S,2S)-2-(1,3-dioxobenzo[f]isoindol-2-yl)cyclohexanecarboxylic acid is an organic compound with the formula C21H17NO4 and a molecular weight of 351.36g/mol.
Nature:
(1S,2S)-2-(1,3-dioxobenzo[f]isoindol-2-yl)cyclohexanecarboxylic acid is a solid with a white to yellowish color. Its melting point is about 220-224°C, and its solubility is low.
Use:
This compound has important application value in the field of medicinal chemistry. It is a compound with a chiral structure and can be used as an intermediate in the synthesis of chiral drugs. In addition, it can also be used as a ligand for the coordination chemistry of iron ions.
Preparation Method:
The preparation of (1S,2S)-2-(1,3-dioxobenzo[f]isoindol-2-yl)cyclohexanecarboxylic acid is not particularly simple. A common preparation method is by reacting 2,3-naphthalenedicarboxylic acid with 2-hydroxycyclohexanone under alkaline conditions, and then further subjecting the resulting product to a deprotection reaction to finally obtain the target product.
Safety Information:
specific safety information about (1S,2S)-2-(1,3-dioxobenzo[f]isoindol-2-yl)cyclohexanecarboxylic acid has not been widely reported, so specific toxicity and safety information need to be evaluated according to the actual situation in the specific use process. During handling and use, general laboratory safety practices should be followed, including wearing gloves, appropriate protective clothing and glasses, ensuring good ventilation, and avoiding inhalation, ingestion or contact with skin. In case of discomfort or accident, seek medical attention immediately and bring complete information on the compound.
Last Update:2024-04-09 21:54:55